Bone marrow mesenchymal stem cells attenuate inflammation and promote angiogenesis in experimental spinal cord injury.

In this experiment, rat bone marrow-derived mesenchymal stem cells (MSCs) were isolated, cultured, and then seeded to the scaffolds, and results showed that 3D GS scaffolds allowed MSCs to adhere, survive, and proliferate. These scaffolds were biocompatible, and MSCs seeded to the scaffolds played an important role in attenuating inflammation, promoting angiogenesis, and reducing cavity formation. The conclusion suggests that GS scaffolds with MSCs may serve as promising supporting transplants for repairing spinal cord injury.