This study points out that human umbilical cord tissue has recently been recognized as an ideal source of mesenchymal stromal cells due to accessibility, vast abundance and safety. The results of injected human umbilical cord tissue derived mesenchymal stromal cells in a rat model of intracerebral hemorrhage demonstrated that the treatment significantly improved neurological function deficits and decreased injury volume.
In addition, the treatment significantly increased vascular density in and these transplanted stromal cells were found to be able to incorporate into cerebral vasculature at 14 days after transplantation, suggesting their ability to inhibit inflammation and promote angiogenesis.
