Pro- and anti-angiogenic molecules and their potential to treat various diseases.

Cancers and various ischaemic and inflammatory diseases all carry the hallmark of pathological angiogenesis. This insight points out that research is leading to the discovery of pro- and anti-angiogenic molecules, and how they affect the related vascular structures of these conditions. These understandings are leading to development of bold new approaches to the treatment of cancer and other diseases.