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SUPPORT NORMAL ANGIOGENESIS†

Regular retail price: $98.00

C-Statin is a product that has been demonstrated to support normal angiogenesis.4 Angiogenesis is the process which promotes the formation of new blood vessels. Recruitment of new blood vessels plays a crucial role in abnormal cell growth and survival.†

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Research on C-Statin

ANTI-ANGIOGENIC, ANTI-TUMOR AND IMMUNOSTIMULATORY EFFECTS OF A NON-TOXIC PLANT EXTRACT (PGM)

Authors: Riordan NH, Meng X, Riordan HD.

ABSTRACT: Recruitment of new blood vessels plays a crucial role in tumor survival and growth. Several agents that act as angiogenesis inhibitors are currently being investigated as anti-tumor agents. Proteoglycan extract (PGM) was tested for anti-angiogenic, immunostimulatory, and anti-neoplastic activity. PGM is a non-toxic extract of the ubiquitous plant, Convolvulus arvensis. In the chicken egg chorioallantoic membrane assay PGM inhibited new blood vessel growth in a dose-dependent manner. Results were 18, 55, and 73% inhibition at concentrations of 50, 100, and 200 mcg, respectively. PGM significantly inhibited tumor growth in the mouse fibrosarcoma (S-180 Kun Ming 3-4 wk old mixed male/female, 10 animals per group, 250-1000 mcg daily doses for 14 days), and mouse Lewis lung carcinoma (C57, 6 wk old mixed male/female, 10 animals per group, 250-1000 mcg daily doses for 14 days) models. Inhibition (54-77% inhibition by weight compared to controls, up to 96.8% by cellular composition) occurred regardless of route of administration: intravenous; intraperitoneal; subcutaneous; and oral. PGM induced lymphocyte growth in a dose dependent manner. The ability of PGM-treated phagocytes to phagocytose yeast cells was 85% greater than controls. We conclude that PGM is a potent angiogenesis inhibitor that has immunostimulatory activity in vitro and anti-tumor activity in vivo and that PGM should be studied further as an anti-neoplastic agent.

Link to Full Text

How Does it Work?

Convolvulus Arvensis Extract

We have developed a proprietary, patented method of obtaining a high-molecular weight extract of bindweed. Through this process, we remove the toxic parts of the plants, and obtain a highly concentrated level of PGMs. The PGMs are what’s responsible for the immunostimulatory and anti-tummor effect.†

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Proven Support for Normal Angiogenesis†

Proteoglycan extract (PGM) was tested for antio-angiogenic and immunostimulatory activity. In the chicken egg chorioallantoic membrane assay, PGM inhibited new blood vessel growth up to 73% (see figures 1 and 2).

Click the link below to see the research surrounding C-Statin!

PGM Paper

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Figure 1: Chicken egg chorioallantoic membrane assay (CAM) with tumor cell induced angiogenesis (control).4*

*Results not necessarily typical.  Individual results may vary.

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Figure 2: CAM with tummor cell induced angiogenesis treated with PGMs!4*

How to take?

  • Take 2-12 capsules per day as part of a healthy diet. Can be taken with or without food.
  • Loading dose = 2 servings AM/PM (6 capsules daily)
  • Maintenance dose = 1 servings AM (2 capsules daily)

Overview:

We suggest talking to your doctor to recommend dosing for your specific needs. In general, it’s best to take 6 capsules/day until you see an effect from the product and continue this dosage until you have achieved your desired results. Responses to the product differ from person to person, some people take more than 6 capsules. As with any new supplement, it is advised to consult your physician before using. If you are using any prescription or over-the-counter medicines, are unaware of your current medical condition, or have any pre-existing medical condition(s), consult with your physician before using this product. There are no known side effects from taking C-Statin.

CAUTION:

Not intended for use by pregnant or lactating women. If you are recovering from a recent surgery, or if you have a heart or circulatory condition, seek the advice of a medical professional before using this product.

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